The family of Alice Gross have been waiting for almost two years for the inquest into her death.
She disappeared from her home in Hanwell on August 28 2014.
Her mother Ros Hogkiss, father Jose Gross and sister Nina are all expected to attend.
The hearing is taking place in front of a jury and is being heard in front of Westminster Coroner, Fiona Cox at the Royal Courts of Justice.
She took the inquest over when Chinyere Inyama, the West London Coroner, requested the move after he left a 30 page file relating to the case on a train.
Alice Gross last moments were captured on CCTV as she walked along a towpath of the Grand Union Canal.
The search to find the missing teenager became the largest search operation by the Metropolitan Police since the July 7th bombings.
Some 600 officers from eight forces were involved.
Her body was eventually found in the River Brent five weeks after she vanished.
The prime suspect was Lativian builder and convicted murderer, 41-year-old Arnis Zalkalns, who had gone missing from Ealing.
His badly decomposed body was discovered hanging in Boston Manor Park three days after Alice's had been discovered.
Detectives later revealed evidence which it said firmly pointed to Zalkalns being responsible for murdering the 14-year -old.
The inquest jury will hear details about the circumstances of Alice's death and several witnesses are expected to be called.
There will also be written statements read to the court.
The purpose of the inquest is to answer four questions; confirm Alice's identity, her place of death, the time and how she came by her death.
It is not the purpose of an inquest jury to determine criminal liability of apportion guilt.
The inquest is expected to last for up to three weeks.