A firefighter was left requiring hospital treatment after a group launched fireworks at emergency services as they tackled a blaze.
London Fire Brigade (LFB) crew were set upon as they responded to reports of a bin fire in Stepney Green on November 5.
The group continued to aim fireworks at emergency services even after police attended shortly after 9.50pm.
One officer was taken to hospital with non life-threatening injuries.
LFB have condemned the suspects, describing their actions as "unacceptable".
Tom George, LFB director of operations, said: "It is unacceptable that firefighters were targeted with fireworks while responding to an emergency 999 call."
He added: "We will not tolerate attacks on firefighters and we will be working with our colleagues at the Metropolitan Police Service to identify those responsible."
Scotland Yard appealed for witnesses to come forward with any information.
A Met Police spokesperson said: "Police were called by London Fire Brigade at 2153hrs on Sunday, 5 November, to reports of a group of people throwing fireworks at fire fighters who were responding to reports of a bin fire at Pattison House, Wellesley Street.
"Police attended. The group continued to throw fireworks at fire crew and police officers before dispersing."
The news comes as LFB announced they attended 17 fires over bonfire weekend believed to have been caused by fireworks.
Anyone who has information should call Tower Hamlets CID by dialling 101, via @MetCC or anonymously calling Crimestoppers on 0800 555 111.