Daniel De-Gale was diagnosed with acute lymphoblastic leukaemia when he was six years old.
He has two years of intense chemotherapy to try and beat the cancer. When he relapsed, his parents were told his only survival would be healthy cells from a donor.
But at that time his changes of finding a match were just one in a quarter of a million.
Beverley and Orin knew they had to raise the number of black people coming forward as donors.
They set up the African Caribbean Leukemia Trust and called on celebrities for help.
It was another four years before Daniel finally found a match. The woman who would give him the gift of life was thousands of miles away was thousands of miles away in the United States.
The first time they spoke was from the ITV London studio.
A short time later they met for the first time, in person, in Detroit. Daniel's journey from diagnosis to finding a donor meant he had ten extra years with his family before he died from multiple organ failure in 2008.
A memorial service brought together those who over the years have supported the ACLT, the people who owe their lives to the organisation and those who knew and loved Daniel.
A young man who during his short life made a major difference and who is still having an impact today.
Orin and Beverley De-Gale and Doreene Carney spoke in the ITV News digital studio to Katie Barnfield.