Tony Pulis has left Crystal Palace by mutual consent - two days before the season has even begun.
He met with chairman Steve Parish after reports of friction after Pulis grew frustrated over a failure to land a number of summer signings.
Assistant manager Keith Millen will be in temporary charge for Saturday's trip to Arsenal.
The club is yet to comment.
Pulis guided Palace to 11th place last season. making it the first time the club have managed to stay in the Premier League after being promoted
Tony Pulis has left his post as manager of Crystal Palace, Press Association Sport understands.
It was widely reported that Pulis and club co-chairman Steve Parish were holding talks to discuss issues relating to transfer dealings.
According to BBC Sport, Pulis has been frustrated by the club failing to push through deals for various players he targeted to strengthen the Palace squad.
Pulis led Palace to survival in the top flight last season after inheriting a squad in turmoil in November, and was named the League Managers Association's Premier League manager of the year in May.
Crystal Palace co-chairman Steve Parish has hinted that the Eagles are ready to take Wilfried Zaha back to Selhurst Park. Zaha was sold to Manchester United for £15 million in 2013 but his future at Old Trafford is in question as he has failed to shine. In an interview with Sky Sports News Parish insists the 21-year-old winger would be welcome back but stresses the decision is up to Palace boss Tony Pulis - and United.
It's up to the manager, the players we sign. It's not up to me. I'm there to help him get the squad he wants. There's a sentimental value and I loved Wilf as a kid and he did sensational things for us. "I know the fans would like him back and that will play a part, but in the end the manager will decide what we do.
Parish hopes to complete the signing of two players before Saturday's Premier League opener against Arsenal and confirmed the row over player bonuses has been brought to a successful resolution.
Marouane Chamakh has signed a new two-year contract at Crystal Palace, the Barclays Premier League side have announced.
The 30-year-old Morocco international originally moved to Selhurst Park on a one-year deal last summer after leaving former club Arsenal and went on to become a regular fixture in the Eagles' side as Tony Pulis guided them to Premier League safety.
"My priority is to stay here. The adventure here is not over. We've had a good season and built something really, really strong. I hope that will continue", Chamakh told the official programme.
Crystal Palace player Mile Jedinak has scored Australia's second goal in their World Cup match against Holland.
Crystal Palace boss Tony Pulis hailed his side's comeback against Liverpool as "amazing".
Palace scored three times in the last 11 minutes to come from 3-0 down to secure a point in their final home of the season.
"I said the game would open up in the second half, and we'd have a chance," Pulis said.
"Then they get the two and, at 3-0, you're staring down the barrel. When we got the first goal, I thought we'd have a squeak.
"Then everything took off, it was amazing. When the second goal went in, it was just a matter of time until we got the third."
Tottenham Hotspur have apologised after a video mocking Liverpool's title setback at Crystal Palace appeared on their Twitter account.Read the full story ›
Crystal Palace players paid tribute to fans at Selhurst Park after their memorable comeback against Liverpool last night.
Two goals from Dwight Gayle and a strike from Damien Delaney helped Palace fight back from 3-0 down against the Reds and end the season at Selhurst on a high.
What a way to finish the last home game fans have been fantastic all season and really pulled us through it
what a result great comeback tonight never say die attitude!!! gutted couldnt be involved due to illness but great way to end our home games
Incredible scenes tonight! That was some comeback from the boys! Selhurst was absolutely bouncing! Thrilling viewing? http://t.co/DCauAY3HhF
Crystal Palace scored three goals in nine minutes in a sensational comeback which left Liverpool's title hopes in tatters.
The Reds strolled into a 3-0 lead but a deflected shot from Damien Delaney with 10 minutes to go sparked a Palace fightback.
A double from substitute Dwight Gayle sealed a memorable draw to the delight of the home crowd.
Crystal Palace manager Tony Pulis has won the Barclays Manager of the Month award for April.
Palace beat Cardiff City, Aston Villa, Everton and West Ham to secure Premier League safety.
The victories followed a win against Chelsea during their five-match winning run.
"It's not about me really, it's about everyone at the football club and that includes my staff, the players, the chairman and directors and the wonderful support we've received all season," Pulis said.
"To win five on the bounce is a wonderful achievement at any football club, irrespective of the name, and it's a testament to the players for their attitude and commitment towards keeping this club in the Premier League."