The regeneration of Elephant and Castle will bring thousands of jobs and homes to this part of the capital, London Mayor Boris Johnson said, as the project officially kicked off today.
Mr Johnson added:
Developments like this at One the Elephant, and next door on the Newington Butts site, are just the beginning, bringing quality homes into the area and helping to rejuvenate the high street.
Alongside the improvements to transport links we're seeing the start of a real renaissance for the area.
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Protesters also climbed on top of a Docklands Light Railway train at Canary Wharf station.
Extinction Rebellion says that as 10 days of protests come to an end, more are planned for later this year.
The Extinction Rebellion demonstrators glued themselves to entrance of the exchange with LED signs reading "climate emergency".