Southern Railway said it expects to run three quarters of its normal service during a fresh 24-hour strike by some of its staff later this week.
Members of the RMT union will walk out on February 22 in a long-running dispute over the role of conductors.
Southern said that during the last RMT strike in January, it ran around three out of four trains and expects to operate at least that number again.
Southern said it will make the following changes:
No Southern West London Line services between Clapham Junction and Milton Keynes Central via Kensington Olympia / Watford Junction
No Southern service between Leatherhead and Guildford (four trains a day)
Buses replace Rye-Ashford International shuttle services in the morning and evening peaks. However, there are plans to operate most services between Ashford International and Brighton
Some trains between London Bridge and Brighton, Eastbourne or Littlehampton will not operate
Some services between Brighton and Seaford / Eastbourne / Hastings / Ashford and between Brighton and / Bognor Regis / Littlehampton / Portsmouth Harbour / Southampton Central will not operate, while others will have fewer carriages than normal
Most services that only run between Brighton and Hove will not operate
We will be running as many trains as possible on Wednesday, but our advice to passengers is to expect some disruption and check on our website before you travel. Online journey planners will be updated 24 hours in advance, and passengers were advised to check the Southern website for further details.