Andy Carroll, Adrian and Samir Nasri are to leave West Ham this summer, the club have announced.
The trio, along with Spanish striker Toni Martinez, will depart when their contracts expire at the end of June.
West Ham joint-chairmen David Sullivan and David Gold said in a statement on the club's website: "Andy and Adrian have both been great servants to West Ham United throughout their time at the club and we thank them for their loyalty and commitment to the claret-and-blue cause.
"Both have provided us and our fellow supporters with some unforgettable moments, whether they were sensational scissor kicks and unstoppable headers in Andy's case, or penalty saves and goals in Adrian's.
"They can both be assured of warm welcomes whenever they return to London Stadium and we wish them, as well as Samir Nasri and the young players whose contracts are up this summer, the very best for their future careers."
West Ham forward Andy Carroll has had ankle surgery, which will rule him out for the rest of the season, it is understood.Read the full story ›
Andy Carroll may have played his last game for West Ham after yet another injury setback.
The former England striker has been missing from the Hammers squad for the last two matches, and manager Manuel Pellegrini has now revealed Carroll has an ankle problem.
Carroll, 30, will be out of contract in the summer and, having started only three Premier League games all season, he is not expected to be offered a new one.
Pellegrini was unable to put a timescale on Carroll's return but his past injury record has raised fears that he will not appear again this term.
"Andy Carroll has an ankle problem," said Pellegrini. "How serious we don't know, I cannot tell you.
"We need to wait for some medical examinations and after that we will know."
Carroll joined West Ham from Liverpool in 2012, initially on loan before agreeing a £15million permanent switch on a six-year contract.
In that time he has started only 84 Premier League matches out of a possible 266 due to a catalogue of injuries.
The England striker is a free agent in the summer and could be available for as little as £2m in the January windowRead the full story ›
Andy Carroll admitted the point he snatched for West Ham against Stoke could be vital but insisted: "We're not safe yet".
Fit-again striker Carroll climbed off the bench to volley a last-minute equaliser on his first appearance since the turn of the year.
A 1-1 draw left the Hammers seven points above the Premier League drop zone with five games left and, crucially, kept Stoke in the bottom three.
"I thought we played well throughout," said Carroll. "We took points off them, and it's a point for us, so it was a good result in the end.
"We've still got five games left and we've got to win them as no one is safe. It's tough at the minute and we've just got to keep working."
In the week following Pep Guardiola's Manchester City slickers being confirmed as champions it was something of a throwback to see two old-fashioned targetmen, Carroll and Peter Crouch, on target at the London Stadium.
Crouch, also a substitute, pounced on a mistake by goalkeeper Joe Hart - in front of England manager Gareth Southgate - to prod Stoke ahead with 11 minutes remaining.
PL team news: Sturridge, Carroll and Barkley could all feature plus the rest of the Premier League weekend team news.Read the full story ›
Andy Carroll faces another lengthy spell on the sidelines after West Ham manager David Moyes confirmed he may require surgery.
Carroll, linked with a move to Chelsea during the transfer window, has been absent from West Ham's recent fixtures with an ankle issue.
The Hammers had hoped the 29-year-old, whose career has been scuppered by a host of injuries, would be missing for only a number of weeks.
But Moyes, speaking ahead of his side's Premier League clash against Bournemouth on Saturday, conceded that he could now be ruled out for months.
"We found out yesterday after Andy went for a scan and it showed up that he has got a problem," Moyes said. "We are not sure whether the ankle will need an operation or not.
"We are getting two or three specialists to look at it and then we will be able to make the correct decision. Hopefully we will know within a week."
West Ham striker Andy Carroll has an ankle injury and faces a possible lengthy absence, Press Association Sport understands.
Carroll has been linked with a move to Premier League champions, but now any move in January appears to be unlikely after a scan revealed the severity of the injury on Thursday.
Surgery is among the options being considered and, if 29-year-old Carroll underwent an operation he would be out for months, rather than weeks.
Hammers boss David Moyes is likely to address the matter in his media conference on Friday ahead of Saturday's Premier League clash at home to Bournemouth.
Carroll has not played since January 4 against Tottenham.
Moyes was at Chelsea's FA Cup replay with Norwich on Wednesday night, apparently watching Belgium striker Michy Batshuayi.
Batshuayi scored Chelsea's first goal in more than five hours, but his overall performance was underwhelming as he frequently squandered possession.
David Moyes has denied West Ham are ready to sell Andy Carroll this month.
The club have reportedly fielded interest from Chelsea and are prepared to listen to offers for the striker before the end of the January transfer window.
Carroll was not included in the squad on Tuesday as West Ham edged into the FA Cup fourth round after a 1-0 replay win over League One side Shrewsbury.
"They've not made contact with me. If they've made contact with someone else I don't know about it," Moyes said.
"Andy Carroll is part of my squad. I want to add to my squad, not lose anybody. There's been a lot of rumours regarding a loan but as far as I know it's not officially come from Chelsea."
Asked if he had any indication Carroll wanted to leave West Ham, Moyes added: "No. At the moment Andy has an ankle injury.
"He had an injection around 10 days ago and we hope that will settle and he will be available again as soon as possible."
David Moyes saluted Andy Carroll after his decision to recall the striker paid dividends against West Brom last nightRead the full story ›