Sofia Sanchez had her first birthday wish granted which was to meet Drake now she receives her second birthday wish, a heart transplant.
Superfan Sofia Sanchez, who was awaiting a heart transplant, had been longing to meet the rapper.
He was handed the top prize by Prince Michael Jackson, the son of the late singer.
Canadian singer Drake has criticised the Grammy Awards for only nominating him in categories for rap artists.
The star said reports of alleged altercation at a central London show are "devastating" and he would never disrespect Muslim fans.
The Toronto rapper's latest album Views was streamed more than 2.45 billion times, making it the most popular of the year in the UK.
The Canadian singer surpassed Michael Jackson's previous record of 11 AMA nominations.
Mr Bean has been resurrected in the latest parody of Drake's Hotline Bling video to hit the Internet.
"B*tch, I'm Madonna," said the 56-year-old before leaving the stage.