From a shortlist with works featuring messages on politics, climate change and identity, Dave's family reflection was the pick of 2019.
The prestigious award will see 12 albums battle it out for the crown of best contemporary music album of the last 12 months.
The most coveted prize in music was awarded to Wolf Alice in a ceremony at the Eventim Apollo at Hammersmith, London.
Sampha has been crowned the winner of the Mercury Prize for his album Process.
James Blake has won this year's Mercury Prize for music for his album Overgrown.
He beat 11 other acts, including David Bowie and bookies favourite Laura Mvula.
Other nominees included previous winners Arctic Monkeys and singer-songwriter Jake Bugg.
The £20,000 prize is open to British and Irish acts and aims to reward the best album of the year.
Click here for more on this year's winner
David Bowie's comeback album has been shortlisted for the Barclaycard Mercury Prize alongside the Arctic Monkeys, Jake Bugg and Rudimental.
Plan B, Richard Hawley and Jessie Ware are among the contenders for the 2012 Barclaycard Mercury Prize.