Roberto Bautista Agut claimed a shock victory over world number one Novak Djokovic 1-6 7-5 6-3 at the Miami Open.
The Spaniard took time to find his rhythm, losing his first two service games and finding himself 5-0 down in the first set.
Djokovic, a six-time winner at the tournament, took 33 minutes to take a one-set lead, and broke the first game in the second set.
But Bautista Agut, ranked 25th in the world, bounced back after a rain delay and drew the game level at 1-1.
Two further breaks of serve were all that was needed for Bautista Agut to take the match and set up a quarter-final tie with reigning champion John Isner.
Isner saw off Britain's Kyle Edmund 7-6 (5) 7-6 (3), the match finishing in controversial fashion when a shout of "out" from the crowd put Edmund on the back foot.
Felix Auger-Aliassime knocked out 17th seed Nikoloz Basilashvili 7-6 (4) 6-4, while Borna Coric spent nearly two hours on court as he prevailed against Nick Kyrgios 4-6 6-3 6-2.
Elsewhere Kevin Anderson saw off Jordan Thompson 7-5 7-5, Frances Tiafoe got the better of David Goffin 7-5 7-6 (6) and Denis Shapovalov was taken to a third-set tiebreak but prevailed against Stefanos Tsitsipas 4-6 6-3 7-6 (3).
Novak Djokovic made light work of Rafael Nadal to brush aside the Spaniard and win the Australian Open.Read the full story ›
Novak Djokovic will play Rafael Nadal for the 53rd time in the Australian Open final on Sunday after crushing Lucas Pouille for the loss of only four games.
Of the world number one's 24 grand slam semi-final victories, only the one over an injured Marin Cilic at the US Open in 2015 was more comprehensive than this 6-0 6-2 6-2 demolition, which lasted just an hour and 23 minutes.
Frenchman Pouille, who had never faced Djokovic before, had made it through to the last four of a slam for the first time but was left helpless in the face of such a brilliant performance.
Djokovic said: "It's definitely one of the best matches I ever had on this court. Everything worked the way I'd imagined it and even more so. Tough one for Lucas but he had a great tournament and I wish him all the best for the rest of the season."
The narrative at the start of the tournament was supposed to be about the next generation making their mark, but Djokovic and Nadal conceded just 10 games in the semi-finals between them.
The considerable consolation is that the stage is now set for another chapter in one of the great tennis rivalries, and their first slam final since the 2014 French Open.
Djokovic takes a 27-25 lead into the contest having won their last meeting in typically epic fashion in the last four at Wimbledon last summer. The last time they met here, meanwhile, in the final in 2012, Djokovic won after five hours and 53 minutes in the longest slam final in history.
Alexander Zverev landed the biggest win of his career by shocking Novak Djokovic to win the ATP FinalsRead the full story ›
Novak Djokovic made it two wins from as many matches at the ATP Finals with a 6-4 6-1 victory over Alexander Zverev.
The world number one was pushed harder by 21-year-old Zverev than he had been during his routine win over John Isner on Monday.
Zverev, the third seed, even forced two break points at 4-4 in the first set.
However, Djokovic fended them off before breaking to take the set, and Zverev's challenge promptly evaporated in the second as the Serbian moved a step closer to a sixth title at London's 02 Arena.
Novak Djokovic stayed on course for back-to-back Grand Slam titles by beating Kei Nishikori to set up a US Open final against Juan Martin del Potro.
With conditions much cooler than they have been for most of the tournament, Djokovic finally looked comfortable on Arthur Ashe Stadium and responded with his best performance to defeat Nishikori 6-3 6-4 6-2.
The sixth seed will contest an eighth US Open final looking for his third title and 14th overall at slams, which would put him level with Pete Sampras.
Novak Djokovic avoided suffering the same fate as Roger Federer as he overcame the never-say-die John Millman to reach the semi-finals.Read the full story ›
Novak Djokovic became the first singles player to complete the Golden Masters as he beat Roger Federer in the Western & Southern Open final.
The Serbian cruised to a 6-4 6-4 win over his long-running rival to clinch the only ATP Masters tournament he had yet to win.
Five years after securing his eighth different crown, the former world number one was able to claim the elusive ninth and final title of the set, having lost five previous finals in Cincinnati - three to Federer.
Djokovic did not win a set in either of those defeats but he took the first this time.
The Swiss took an early break in the second, but a shaky service game and a rare double fault handed the break right back to his opponent.
Federer struggled with his footwork and was unable to capitalise on Djokovic's second serve, opening the door for the Serbian's decisive break at 4-3.
Djokovic held his nerve, sealing the win on his first match point after just an hour and 25 minutes on court.
Speaking on court after the match, Djokovic said: "Obviously it's a very special moment to stand here for the first time with the winning trophy here in Cincinnati.
"The hard times I went through, it's been a rollercoaster ride in my career with injury, taking time off and having a surgery earlier this year. This seems a bit unreal to be back at this level."
Novak Djokovic overcame Rafael Nadal in another epic Wimbledon semi-final.Read the full story ›
Djokovic will return to Queen's after an eight-year hiatus as the former world number one begins his grass court season.Read the full story ›