On Sunday, thousands of spectators are expected to line the streets from Newcastle to South Shields, to enjoy the atmosphere of one of the most prominent fixtures on the North East calendar.
Read more: Great North Run 2018 Hall of Fame
Last year, organisers said 43,000 runners attempted the 13.1-mile Great North Run. Sir Mo Farah sealed a record-breaking fifth victory, after winning the elite men's race with a time of 59 minutes and 26 seconds.
Familiar faces will be standing on the start line, encouraging those anticipating the journey ahead. They include Jill Scot and Steph Houghton from England Women's Football team that reached the World Cup semi-finals this year, plus Cricket World Cup winner Mark Wood.
We've been following the stories of some of the amazing people preparing for this year's half marathon:
Lee Williamson, from Sunderland, ran the race in 2002, but this year he's doing it in a wheelchair.
He suffered a stroke 12 years ago which left him paralysed down one side of his body.
Charli Hopper is 11-years-old and from County Durham.
She had open-heart surgery as a baby after being born with three holes in her heart. Since then, she's become a fundraiser, often collecting for charities and food banks.
Ahead of taking part in the Junior Great North Run, she's been telling us her story.
We've followed the weight loss journey of Darren 'Dibsy' McClintock, from Teesside, since last year.
Weighing 40-stone, he was diagnosed with a serious heart condition. Doctors told him that to even contemplate surgery, he would need to lose a significant amount of weight. He's since shed 19-stone with the help of his trainer, Mike Hind.
His next challenge? The Great North Run, of course.
Ed Ammon was just 39 when he lost his battle with leukaemia.
Described as a funny, strong man loved by everyone he met, his amazing friends are running the Great North Run for the Anthony Nolan Trust in his memory, dressed in cricket whites...
And Sunderland Olympian Aly Dixon has rewritten the record books - just in time to return to a home crowd.