Support from across the region has been pouring in for Boris Johnson who remains in intensive care after his coronavirus symptoms persisted.
The Prime Minister was taken to St Thomas' Hospital in London on Sunday night ''as a precaution''.
Mr Johnson has been given ''oxygen support'' at hospital, but has not been on a ventilator, a Cabinet minister said.
Conservative colleagues, opposition MPs and world leaders have shared messages of support.
Guy Opperman, MP for Hexham was among the first of the Tyne Tees region's politicians to react on Twitter:
He said: ''Thoughts and prayers for Boris Johnson and his family tonight. Get well soon. We need you to beat Covid-19 and get back to 10 Downing Street.''
The Conservative MP added, that he too had spent time at St Thomas' after collapsing at the House of Commons with a brain tumour in April 2011.
He went on to praise the staff saying: ''Owe my life to the amazing team there. Our PM is in good hands.''
Simon Clarke, MP for Middlesbrough South and East Cleveland also took to Twitter. He said: ''Sending the Prime Minister my thoughts and prayers tonight - and I know I do so on behalf of thousands of people in Middlesbrough South and East Cleveland.''
Chi Onwurah, MP for Newcastle Central said: ''Very sorry to hear this. I hope the Prime Minister recovers quickly and I wish him and his family all the best.''
Conservative Mayor of the Tees Valley Ben Houchen tweeted: "My thoughts and prayers are with Boris Johnson and his family tonight and I wish him a speedy recovery.''
MP for Redcar Jacob Young tweeted: "#Teesside still behind you Boris - get well soon.'' The message was posted alongside an old photo from the Prime Minister's general election campaign trail which said: ''We love Boris''.