Today many shops and pubs will reopen after weeks of closure, and the public are been urged not to become complacent.
Mr Johnson urged caution during the "major step forward" as a scientist advising the government warned the rules must be followed to minimise a possible rebound in case numbers.
Superintendent Emily Harrison, who is leading the Cleveland Police's COVID response, said: “We recognise the easing of restrictions today is another positive step towards a return to aspects of ‘normal’ life.
“We’d urge people to remember many premises are using booking systems so please double check with the venue you plan to attend, think about booking in advance to avoid disappointment.”
“We know anyone organising or attending such indoor events doesn’t need the regulations explained to them and we’ll quickly move to enforcement in these scenarios.”