International Paralympic Committee president Sir Philip Craven said he was proud to welcome the Paralympics back to their birthplace in the UK.
The games were founded in 1948 by Dr Ludwig Guttmann to aid the rehabilitation of injured Second World War personnel.
Sir Philip Craven told 1,6000 people at a special ceremony in St Paul's Cathedral that he was "chuffed" the games were returning to the UK.
His comments come as the third of the flame lighting events took place in Edinburgh last night. Later today the final Paralympic flame will be lit in Cardiff.
The Paralympic torch is on its way to the Olympic Park in Stratford for the opening ceremony of the Games.
Wounded veterans set to compete for Britain at the Paralympics have paid tribute to sport for rescuing them from despair at their injuries.
In all sport, we categorise humans according to their physical attributes, it is just a bit more detailed at the Paralympics.