Severely ill patients will only be given early access to experimental drugs after they have passed "second stage clinical trials", the Health Secretary has told Daybreak.
Jeremy Hunt sought to reassure severely ill patients they would have access to potentially groundbreaking medicine only if it was deemed "safe" by UK Government experts.
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Which? and the Access to Cash Review have written to Chancellor Sajid Javid urging action.
The president of the European Commission has told MEPs he believes achieving a deal is possible but the risk of no deal is "palpable".
The legal battle in the Supreme Court features on many of Wednesday’s front pages.