The Mid-Staffs scandal, in which appalling conditions lead to hundreds of patients dying prematurely, should be "a turning point" in NHS culture, Jeremy Hunt has said.
In a speech at the Virginia Mason Hospital in Seattle, the Health Secretary outlined plans to create a "more open, compassionate and transparent culture" in the health service.
It is my clear ambition that the NHS should become the safest healthcare system anywhere in the world.
I want the tragic events of Mid Staffs to become a turning point in the creation of a more open, compassionate and transparent culture within the NHS.
We now have a once-in-a-generation opportunity to save lives and prevent avoidable harm - which will empower staff and save money that can be reinvested in patient care.
Hospitals are already 'signing up to safety' as part of this new movement - and I hope all NHS organisations will soon join them.
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Teenagers, aged 13 and 14, were taken to hospital on Friday morning but passed away, South Yorkshire Police said.
Eleven people remain in hospital.
The 22-year-old wore the full uniform, including hairnet, in Middlesbrough.