Citizens Advice has said an extra room "can be a lifeline" for a disabled person, calling it "as vital as a guide dog or a wheelchair".
Chief executive Gillian Guy said for many people a spare room "is essential to their wellbeing" as it is needed for dialysis equipment or room for a carer.
Ms Guy said: "Many sick and disabled people have bedrooms which have been adapted to help them to cope with their condition.
"Moving disabled people out of their houses is not only a potential risk to their health, but can cost the individuals affected and councils significant amounts of money if they need to start from scratch in a new home."
More top news
Princess Cruises said seven passengers and five crew members on the Coral Princess had tested positive for Covid-19.
Boris Johnson’s hospital stay leads Monday’s papers.
The Prime Minister was transferred to hospital as a “precautionary measure” on the advice of his doctor, according to Number 10.