Instrumental in organising the human trafficking and slavery conference was Cardinal Vincent Nichols, the head of the Roman Catholic Church in England and Wales.
Like Pope Francis he wants the voices of victims to be heard more clearly.
When the conference was over, ITV News' Julie Etchingham asked the Cardinal to assess the impact of the Pope's message that trafficking was a crime against humanity:
To see Pope Francis in the flesh - so famous, so familiar - his pewter cross hanging starkly against his white robes was extraordinary.
Pope Francis has exclusively spoken to ITV News about human trafficking and had a message for those responsible for the crime.
Top police officers, religious leaders and politicians from around the world have gathered in the Vatican to eradicate people trafficking.