Victorino Chua failed to show any remorse for murdering and poisoning patients at Stepping Hill Hospital, police say.
Chua, 49, was jailed for at least 35 years, meaning he will not be considered for parole until he is in his mid 80s.
Speaking after sentencing, Detective Superintendent Simon Barraclough said: "He's consistently failed to show any form of emotion during this process and any form of remorse for what he's done.
"And in fact even through the lengthy process of sentencing this morning, there was not a flicker of emotion on his face apart from what appeared to be a general contempt for all the proceedings on going."
Kathleen Murray told GMB she woke up 'shaking uncontrollably' after being poisoned by Victorino Chua who was the nurse on duty that night.
ITV News has uncovered doubts over how qualified Victorino Chua was before he came to the UK and poisoned patients.
There are suspicions Chua may not have been a qualified nurse