"Serious failings" that led to the death of one-year-old William Mead have "significant implications for the rest of the NHS", Health Secretary Jeremy Hunt has said.
A "lack of understanding of sepsis" and "limited sensitivity" in the questionnaire used by NHS 111 workers have been identified as failings, he added.
Mr Hunt said it was difficult for clinicians to spot sepsis but there has been a renewed push to educate GPs in the signs.
He said there was also scope for a public awareness campaign to help parents spot the "tell-tale signs" of the deadly infection.
Health Secretary Jeremy Hunt promised the parents of William Mead in a private meeting that he'll push for reforms to the NHS 111 helpline.
Mother of baby who died from sepsis as a result of a chest infection believes her son would still be alive if she'd got the right advice.
The NHS non-emergency helpline cannot identify when children and babies have potentially deadly illnesses, according to a report.