Three wards have been closed at a hospital after a major swine flu outbreak affected 14 cancer patients.
Leicester Royal Infirmary is trying to contain the spread of the virus, which was responsible for the flu pandemic in 2009/10.
The H1N1 swine flu strain is one of the dominant flu strains this winter and the current winter flu jab offers protection against it.
Glenfield Hospital in the city is also treating three seriously ill patients with swine flu, who are receiving extracorporeal membrane oxygenation (ECMO) treatment.
They were brought to Leicester from other parts of the country.
All 14 patients remain in isolation either in side rooms or on bays, a statement from the University Hospitals of Leicester NHS Trust said.
All patients are currently being treated with antiviral medication.
Staff are following protocols for preventing the spread of infection, including wearing masks, gowns and gloves and washing hands regularly.
On Monday, it was thought three people on the wards might have flu, and because these patients have very little immunity, it was decided to swab all patients and 14 were confirmed as positive.
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