Pope Francis has taken 12 refugees from Syria - including six children - with him on his plane back to Rome, according to the Vatican.
In a statement, the Vatican said the pontiff "desired to make a gesture of welcome" regarding refugees.
Three families of refugees, reportedly selected from lots drawn, boarded the Pope's plane as it left the Greek island of Lesbos, the statement said.
All of the refugees were Muslim - two families from Damascus and one from ISIS-controlled Deir Azzor - and will be looked after by the Sant'Egidio Christian community once they arrive in Rome.
As Pope Francis completes his five-hour trip to Lesbos to visit refugee centres, here is a picture roundup of the symbolic tour.
Countless refugees have passed through Lesbos on their way to mainland Europe over the last few years, many not surviving the journey.