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Chancellor George Osborne and other ministers are speaking on the economic consequences to the UK of pulling out of the EU.
Their comments come ahead of the release of Treasury report that warns British families could eventually be £4,300 a year worse off if the UK models its relationship with Brussels on a Canadian-style trade agreement.
Speaking alongside Osborne are Liz Truss, the environment secretary, and Stephen Crabb, the work and pensions secretary.
Vote Leave has so far said little about the Chancellor's gloomy predictions for Brexit, but Leave.EU thinks it's still a price worth paying.
The Treasury forecasts leaving the EU would leave households quite a lot poorer on average - between £2600 and £5200 a year in 15 years.
George Osborne's comments in The Times come ahead of a Treasury report on cost to the country of pulling out of the EU.