President Barack Obama has declared a state of emergency in the state of North Carolina as it braces for Hurricane Matthew to make landfall.
Officials are warning that the biggest risk could be from storm surges, as high winds on the coastline whip up huge waves.
A state of emergency has also been declared in Florida, South Carolina, and Georgia.
Hurricane Matthew is as serious as it gets. Listen to local officials, prepare, take care of each other. https://t.co/Vaf8Xubs0s
The hurricane skated the edge of Florida, causing less damage than feared as they eye of the storm stayed off the coast, but is now heading northwards.
Matthew - which was a category 5 storm when it hit Haiti last week killing nearly 900 people - made landfall in the States on Friday.
As Hurricane Matthew approaches Florida, its 140-mile-an-hour winds have already left behind a trail of destruction in Haiti.
Residents told to fully prepare for the arrival of the hurricane with warnings its impact could be "devastating".