At least 25 dead in Christian cathedral bombing in Cairo

A relative of one of the blast victims speaks to a police officer outside the scene. Credit: Reuters

At least 25 people have been killed and 49 wounded in a bombing at in Egypt's main Coptic Christian cathedral in Cairo.

The blast took place as a Sunday mass being held in the chapel was about to end.

Most of the victims are thought to be women and children.

The blast took place at Cairo's main Coptic cathedral. Credit: Reuters

A bomb was thrown into a chapel close to the outer wall of St Mark's Cathedral, Egypt's MENA news agency reported.

However witnesses have also said the explosion may have been caused by a planted device.

Angry crowds gathered outside the cathedral. Credit: Reuters

An angry crowd of several hundred people gathered outside the cathedral, chanting anti-government slogans and calling for the sacking of the interior minister, who is in charge of security.

Scuffles broke out with the police when the protesters tried to push through their barricades, but there were no immediate reports of arrests.

Police in full riot gear later arrived at the scene.

A nun stands at the scene inside Cairo's Coptic cathedral. Credit: Reuters

It is the second deadly attack to hit the Egyptian capital within two days.

On Friday, six policemen were killed in a bomb attack claimed by a militant group. There was no immediate claim of responsibility for Sunday's attack.