Between 80,000 and 100,000 people may be evacuated from besieged east Aleppo, Turkey's deputy prime minister Veysi Kaynak has said.
The first convoy of buses has today left the devastated rebel-held enclave carrying around 950 people.
Thousands more are anxiously waiting to be evacuated to relative safety as government forces move in to re-take the territory.
Mr Kaynak has warned there are not enough shelters in Syria's Idlib province, where the evacuees are being brought, to house all the refugees from the city.
He said that they are considering setting up a second refugee shelter inside Syria to meet the demand.
Tens of thousands of civilians desperate to leave Aleppo were left stranded for 48 hours over the weekend after a ceasefire deal broke down.
Dubbed the People's Convoy, aid workers intend to take medical supplies to a new children's hospital in Syria.
Watch all of ITV News correspondent Dan Rivers' reports on the end of the battle for Eastern Aleppo and the evacuation from the city.