All hospital patients in eastern Aleppo has been evacuated, the International Committee of the Red Cross said.
In a tweet, the ICRC wrote: "The last hospital in Eastern #Aleppo is now empty. All patients have been evacuated, along with other people in need of urgent medical care."
Thousands of Syrian civilians were left waiting in falling snow after the evacuation from the rebel-held area of Aleppo stalled on Tuesday.
The evacuation began again on Wednesday and a local news service, run by the Lebanese group Hezbollah, claimed the operation would be completed by the end of the day.
Tens of thousands of civilians desperate to leave Aleppo were left stranded for 48 hours over the weekend after a ceasefire deal broke down.
Dubbed the People's Convoy, aid workers intend to take medical supplies to a new children's hospital in Syria.
Watch all of ITV News correspondent Dan Rivers' reports on the end of the battle for Eastern Aleppo and the evacuation from the city.