There have been 15 further deaths related to Covid-19 and an additional 528 confirmed cases in Northern Ireland.
It brings the total number of coronavirus-related deaths in Northern Ireland to 774, according to figures from the Department of Health.
There are 391 confirmed Covid-19 inpatients in the hospital system, with 53 of those in intensive care.
There are now 22 beds available in ICU, and 101 beds in the wider hospital system, officials said.
Meanwhile, people arriving in Northern Ireland from Denmark must self-isolate after the UK introduced a travel ban on the country following an outbreak of Covid-19 in mink.
While the mutated strain is not believed to be more dangerous, public health officials fear it could undermine the efficacy of a future vaccine.
The UK Government announced that from 4am on Saturday, all non-British national or resident travellers who have been in or transited through Denmark in the last 14 days will be denied entry into the UK.
Any UK citizens arriving into Northern Ireland from the country since October 23 are now legally required to self-isolate for two weeks, along with all members of their household.
The inclusion of all household members in the restriction means these self-isolation rules are stricter than normal travel-related quarantine requirements.
Northern Ireland's chief medical officer Dr Michael McBride said: "Self-isolation for anyone who has been in Denmark is a mandatory requirement and it applies to all members of the household.
"This is an emerging picture and a precautionary approach is required at this early stage.
"We are in very close contact with public health colleagues in Great Britain and the Republic of Ireland.
"Minister (Robin) Swann has also been in contact with his Republic of Ireland counterpart Stephen Donnelly.
"Advice and guidance have been issued to health service colleagues in Northern Ireland.
"The UK authorities are working closely with international partners to understand the changes in the virus that have been reported in Denmark. A programme of further research in the UK will inform risk assessments."
Officials will contact anyone in the UK who has been in Denmark in the last fortnight to ensure they also self-isolate.