Two female doctors have appeared at Cardiff Crown Court accused of the manslaughter of a 12-year-old boy in their care.
Dr Joanne Rudling, 45, and 42-year-old Dr Lindsey Thomas are both charged with manslaughter after the schoolboy died suddenly at his home.
The GPs both worked at Abernant surgery in Abertillery where Ryan Morse was treated.
Ryan had Addison's Disease which causes progressive anaemia, low blood pressure, weakness and discolouration of the skin.
He died suddenly at his family home in Brynither, Abertillery on 8 December in 2012.
Rudling is also accused of making false entries into Ryan's medical records, after allegedly entering notes two days after the boy's death, but making them look like they'd been entered on the day his mum rang in for a consultation.
She is also accused of incorrectly noting his genitals had "changed colour" when his mother, Carol, had specifically said they were "black" in colour.
Mrs Justice Nicola Davies told the jury at Cardiff Crown Court: "Ryan Morse was born on the fifteenth of December 1999, and died on the eighth of December 2012. The cause of death was Addison's Disease.
"The defendants are two GPs who work at Abernant surgery in Abertillery. Each doctor is charged with manslaughter.
"It is the crown's case that it was the actions of each doctor that lead to his death."
Thomas, from Tredegar, denies one count of manslaughter.
Rudling, from Pontprennau, Cardiff also denies manslaughter and trying to pervert the course of public justice.