Wales had the highest rate of winter deaths last winter compared to anywhere else in the UK, according to The British Lung Foundation.
The charity said 32.8% more people died in the winter of 2017/2018 compared to the summer of the same year.
According to their figures, that makes the number of excess winter deaths last year the highest recorded since the winter of 1975/1976.
Head of the British Lung Foundation in Wales, Joseph Carter, said "respiratory disease continues to be a huge challenge in Wales".
According to the charity, respiratory diseases were the primary cause of winter deaths last year.
Responding to the figures, a Welsh Government spokesperson said: “Winter death figures are prone to fluctuation and should be treated with caution". They added that "the reasons behind deaths are complex and varied".
The figures came on the same day Vaughan Gething released a statement with an update on this year's winter pressures.
The Health Secretary said: "Following the evaluation of winter 2017/18, there is increased recognition of the need for national leadership and support".
Addressing the demands on the service last winter, the Health Secretary said: "We have been open that last winter was exceptionally difficult and we saw spikes in demand which, at times, were unprecedented, which impacted on the ability of services to manage and cope with demand and saw performance against key indicators deteriorate".