Over half of 16-25 year olds in Wales think social media creates an "overwhelming pressure" on young people, according to the Prince's Trust Cymru.
New figures from the group suggest nearly half (47%) of 16-25 year olds in Wales say comparing their life to others on social media makes them feel "inadequate".
A further 20% of those surveyed said seeing the lives of their friends online "always" or "often" made them feel "panicked".
The Director of the Prince's Trust Cymru said the figures show "nothing has happened" over the past year to improve the way young people feel about their lives.
In separate research, by the Children's Commissioner for Crime, it was found school pupils in Wales feel that many parents and teachers do not understand the online activities and platforms they use.
Students said they felt parents and teachers were therefore ineffective with their support.
During a 12 month consultation on cyberbullying, with more than 400 schoolchildren, the group said they wanted more opportunities to share their experiences of cyberbullying. As well as their anxieties about online life with their peers in safe spaces.
The findings published today on Safer Internet Day, also call for pupils to be empowered to set up Cyber Action Groups - advising teachers and parents about the latest apps and how young people use them.
Professor Sally Holland, the Children's Commissioner, said young people are increasingly "familiar with negative online experiences".
Pupils at Rhyl High school have recently started running drop-in sessions that provide peer-to-peer support on bullying, including cyberbullying.
Cerys, a 16-year-old pupil at the school said: "When you're being cyberbullied there's no escape from it".
"You've got messages or posts about you, which isn't fair because you've got nowhere to escape, and that's why it's becoming just as serious as bullying in school, and physical contact".