Boris Johnson is facing an uphill struggle to get the last-minute Brexit deal he struck with the EU through the Commons.
Following days of intense negotiations, the Prime Minister announced an agreement had been reached with Brussels as he headed to a summit of EU leaders on Thursday.
Key allies the DUP said they are standing firm over its objections to the Government's Brexit stance.
On Thursday afternoon, MPs backed a motion to hold a special sitting of Parliament on Saturday - the first in 37 years.
Meanwhile Welsh politicians, parties and organisations have given their snap judgements on proposed new deal.
The First Minister Mark Drakeford said it would "make Wales poorer".
The Country Land and Business Association (CLA) said the news would be welcomed by Welsh farmers who, they say were "fearing" the consequences of a no-deal Brexit.
The proposed deal finally provides us with some certainty, that could in turn help unlock much needed investment to get the rural economy moving again.
Plaid Cymru said they wanted the UK Government to release Brexit impact assessments, which look at the effect the deal would have on things like trade and the economy.
This deal will define our economy, society and children’s future for generations – to vote on it blindfold without any idea of its impact would be deeply irresponsible.
The Welsh Conservatives described the deal as "fair and balanced" which delivered on the 2016 election.
This deal ends the uncertainty currently faced by Welsh businesses and communities, will allow us to take full advantage of the benefits that Brexit will offer and my Assembly colleagues and I welcome this news and are fully behind the Prime Minister.
However, back in Westminster, the stance of the DUP is important because the party wields influence over some hardline Tory Brexiteers and Mr Johnson is far short of a majority in Parliament.
Labour leader Jeremy Corbyn was quick to dismiss the deal.
This is a day where the Prime Minister seems to have made a deal with the European Union which doesn't give us the complete freedom of movement between Britain and Ireland because it creates a customs union border down the Irish Sea.
Mr Corbyn also said he does not "suspect" Saturday will present a chance to get a confirmatory referendum through Parliament.
Asked if he would back a second referendum on Saturday when speaking in Brussels, he told reporters: "It won't come up on Saturday, I suspect.