The Welsh Government has announced the regulations that will come into force during the fire-break, including which businesses must close.
It comes almost 24 hours before Wales enters the two-week lockdown, which aims to curb the rising number of coronavirus cases.
On Thursday, figures revealed there were 1,134 new cases identified over 24 hours, with seven further deaths of people who had the virus.
Businesses and workers across the country have been voicing concerns about the new rules and how they will impact their livelihoods.
So, what will the Welsh fire-break look like?
Where will be closed to the public?
Pubs, bars, restaurants, cafes, holiday accommodation, shopping centres and arcades, markets, places of worship, crematoriums and community centres will be required to close with some exceptions.
However, the following businesses and services must shut their doors completely:
Hairdressers, barbers, nail and beauty salons, massage therapy providers, tattoo and piercing studios
Cinemas, theatres, nightclubs, bingo and concert halls and casinos
Car dealerships, betting shops, garden centres
Leisure centres, gyms, swimming pools and spas
Sports courts, skate parks, skating rinks, bowling greens, golf courses, sports pitches, bowling alleys, amusement arcades and indoor play areas
Museums, galleries, funfairs, amusement parks and theme parks, visitor attractions
Estate and letting agents, show homes and events or conference venues
What are the exceptions?
Pubs and restaurants
Pubs, restaurants, bars and cafes will be permitted to serve takeaway food and drink.
Holiday accommodation will also be required to shut, unless the person using it is unable to return home.
This includes hotels, bed and breakfasts, camping sites and holiday sites, hostels, apartments and boarding houses.
Places of worship and crematoriums
Places of worship are only allowed to open for funerals, the solemnisation of marriages and formation of civil partnerships and to provide essential voluntary services.
A crematorium may open to members of the public for funerals or burials.
Some community centres will be able to provide essential voluntary or public services including food banks, support for homeless or vulnerable people, childcare, blood donation sessions or other emergencies.
Shopping centres, shopping arcades and markets can remain open to the public for access to some businesses.
What can stay fully open?
Supermarkets, newsagents, post offices, laundrettes and dry cleaners can all remain open, as can hardware stores, bicycle shops, petrol stations, garages, taxi and vehicle hire businesses.
Shops allowed to stay open cannot sell 'non-essential' items, including clothing, books and electronics.
Pharmacies, chemists, dentists, opticians, chiropractors, osteopaths, mental health services, vets, pet shops, livestock markets and funeral directors are also permitted to stay open.
How does Wales' fire-break fare against the Northern Ireland circuit-break?
While the circuit-break in Wales - coined 'fire-break' by the First Minister - will last two weeks, a four-week circuit-break is already underway in Northern Ireland.
The lockdown came into force on Friday 16 October, with pubs and restaurants there also required to shut unless they offer a takeaway service.
However, places of worship, shops and gyms can remain open.
In Northern Ireland, off licenses and supermarkets are not allowed to sell alcohol past 8pm, two hours earlier than the 10pm curfew in Wales.