New genes linked to Alzheimer's

In the largest ever study of its kind, scientists, jointly led by Cardiff University, say they have uncovered 11 new susceptibility genes linked with Alzheimer's disease.

They say the breakthrough will significantly advance knowledge of Alzheimer's, and allow new research to be undertaken.

This discovery will pinpoint new mechanisms underlying Alzheimer's disease...What surprised us most about the findings was the very strong pattern that showed several genes implicating the body's immune response in causing dementia.

We will now turn our attention to people with early onset Alzheimer's - people in their 40s and 50s afflicted with more severe forms of the condition. Their genetic architecture may hold the key to finding yet more genes involved in Alzheimer's.

– Julie Williams, Cardiff University Head of Neurodegeneration