Public Health England (PHE) says it is working with NHS partners and Bristol City Council after a further confirmed case of meningitis B in a Bristol student.
The organisation says the unnamed patient is recovering well in hospital.
The student used to attend the same school as Bristol student George Zographou who died from meningitis B last month.
ITV West Country understands the boy recognised his symptoms after what George went through.
PHE says close contacts of the student have been followed up and offered an antibiotic to reduce the risk of others becoming infected.
The Men ACWY vaccine for teenagers was introduced in 2015.
Since then the vaccine has been offered to pupils in Year 9 in schools, with a catch up campaign being rolled out for older pupils (Years 10 – 13) and university ‘freshers’.
PHE says students in these age groups who are unsure if they have had the vaccine should contact their GP surgery.
The organisation also says people should be aware of the symptoms of meningococcal disease.