A man died earlier this morning in an incident involving police firearms on The Portbury Hundred (A369) in Portishead, Avon and Somerset Police have confirmed.
The road has been sealed off.
Police have confirmed the incident is not terror-related.
An eyewitness claims he saw police shoot into a car that had been stopped.
Avon and Somerset Police say motorists will not be able to access Portishead from Junction 19 of the M5.
"We have closed off the Portbury 100 (A369) following an incident earlier this morning. The air ambulance has landed.
"We anticipate the road will remain closed for some time."
The Independent Police Complaints Commission says it has been notified of an "incident" by the force.
More to follow...