The RSPCA received more than 1,600 calls about neglected, abandoned and stray exotic animals in the West Country last year.
Calls to the animal welfare charity's cruelty hotline increased from 2017, according to annual figures released today (Thursday 25 April).
Across England and Wales exotic animals accounted for more than 40 calls a day, or more than one every hour.
The charity says one reason behind the suffering of exotic pets is that owners don't research how to take care of them properly.
This results in them escaping, being abandoned or neglected.
West Country figures:
In July 2018 a dog walker found two snakes with burns all over their bodies in Cornwall.
One had to be put down "to stop any more suffering" but the second survived and has since recovered, according to the charity.
RSCPA exotics officer Peter Ferris rescued the animals and said:
The RSPCA is concerned about the welfare of exotic animals that are being kept as pets in the region.
Stephanie Jayson, the RSCPA's senior scientific officer in exotics, said: "Although their numbers are small compared to more common pets, we have real concerns about the welfare of reptiles and other exotic animals kept as pets in this country."
They're now calling for new regulations to tackle the problem.
The charity believes owners often buy the animals because they think they'll be easier to care for than other pets.
It's urging people in the region to research what is required in the care of their pet - including food, equipment, environment and vet care - before taking one on.
To find out more, visit their website.