Ann James has thanked staff and patients and says everybody at the hospital is 'working around the clock' for what she believes will be an extremely busy period.
She says the hospital is quiet at the moment, but a new intensive care ward has been set up in anticipation of a spike in coronavirus admissions.
It has been my absolute privilege to work in the NHS for 30 years, and during that time I have seen staff do some amazing and incredible things. But I have never seen a time like this.
On Thursday it was confirmed that another patient who tested positive for Covid-19 died at Derriford Hospital.