The 'rules of the game have changed' following a vote to leave the EU, business leaders have said.
BusinessWest say although companies are resilient, it may take time before a way forward becomes clear.
James Durie told us this:
University of Bristol added that the funding they receive from the EU is not at threat.
We get tens of millions of pounds a year in funding for our research efforts, that is not at risk today, and I expect the UK to negotiate a deal with those institutions that will continue to offer us access to those funds.
Mayor of Bristol Marvin Rees responded to the result.
I am proud Bristol voted to remain. It says a lot about where we are as a city and our culture. It showed confidence in the strength of our society and our economy, the foundations of our position as global city. The challenge presented by Leave will not stop us from pursing our aspirations for the city – to be a prosperous, inclusive and sustainable city in which no-one is left behind.
We are a global city of mixed heritage. We are a welcoming city. And we are a city of sanctuary. I pledge we will continue to be so.
Britain has made the historic decision to vote to leave the European Union. So what happens next?
Hundreds of people have shown their anger at the EU referendum result, demanding that our borders be kept open for migrants and refugees
There was never much doubt that the South West - the vast EU region stretching from Gloucestershire to Scilly - would deliver a Leave vote