An estimated 132 million coronavirus vaccines were administered in 2021 amid the largest vaccine campaign in British history.
The emergence of the Omicron variant triggered an acceleration of the rollout over the festive season, and more than 1.6 million people received their booster dose in the final week of 2021.
This brought the total UK number of boosted adults to 34 million, including three in four eligible adults in England.
90% of people in the UK over the age of 12 have now had their first dose and 82% have had their second.
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Health Secretary Sajid Javid thanked NHS staff and tens of thousands of volunteers for the success of the rollout since December 2020, and urged more people to get their booster in the new year.
He said: “The Covid-19 pandemic has been one of the biggest challenges our health service has ever faced and our historic vaccination programme has been vital in helping us step up to meet this challenge.”
Mr Javid added that “132 million vaccinations in a single year is astounding and a true reflection of the fantastic work of our NHS and its volunteers”, and said: “I want to thank each and every one of them.
“But we need to make sure people continue to come forward for their life-saving jab.
“As we go into the New Year, make sure you ‘Get Boosted Now’ to kick off 2022 with the best possible protection from Omicron.”
Prime Minister Boris Johnson set the target of offering all eligible adults the chance to get their top-up jabs by the end of January, but following the emergence of Omicron he brought forward the deadline to the new year.
Millions of Britons queued at around 3,000 vaccination centres, and on December 18, NHS England administered a record 830,000 jabs in a single day.
The acceleration of the programme was supported by 750 armed forces workers, and the government suspended the 15-minute observation period following Pfizer and Moderna boosters for most patients.
Vaccines minister Maggie Throup urged more adults to come forward in the new year, and described the rollout as a source of national pride.
Ms Throup said: “The UK Covid-19 vaccination programme is something we can all be proud of – having provided tens of millions of people with protection from this deadly virus over the past year.”
Recent UK Health Security Agency (UKHSA) data shows people who are unvaccinated are up to eight times more likely to be admitted to hospital than those who are fully vaccinated.