Three children are being treated in hospital after escaping a house fire in Powys.
A number of people are unaccounted and police have confirmed there are fatalities.
The children, aged 13 12 and 10, were able to escape the fire at Llangammarch Wells.
They are currently being treated in hospital for non-life threatening injuries.
Dyfed Powys Police and West Wales Fire and Rescue Service were called just after midnight.
Due to the severity of the fire, police said they are currently unable to identify or confirm the number of those who have died.
The cause of the fire is "unexplained".
Community councillor Tim Van-Rees, said:
Chris Davies, Conservative MP for Brecon and Radnorshire, said: "My thoughts are with those affected by the reported fire in Llangammarch.
"I wish the emergency services well in dealing with this terrible situation."