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"We're happy to do what we're doing in terms of cattle control and cattle testing" says NFU spokesman Stephen James.
"But we can't keep doing that and nothing happening about the wildlife".
"Until we get that [badger] cull and control the numbers, this disease is just going to increase".
Farmers' union NFU Cymru claims figures showing a 15% rise in the number of cattle in Wales slaughtered due to bovine TB indicates the disease is "out of control"
It follows nationwide figures published by Defra.
"This has to bea wakeup call to Welsh Government and highlights the urgent to implement a science led policy of badger control in endemic areas of the country rather than the Welsh Government’s vaccination policy" said Stephen James, NFU Cymru deputy president.