Simon Calder, a travel journalist, says the disruption at London Paddington train station could continue into the weekend.
A number of services, including trains to and from south Wales, were cancelled after signalling problems caused major disruption to a line.
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It is estimated there are 50,000 alcohol-related hospital admissions a year, costing the Welsh NHS £120m annually.
This morning will begin cloudy, wet and rather breezy.
Most areas will become dry for a time this evening with clear spells.